بررسی رابطه انفارکتوس میوکارد با بروز سرطان

Background and purpose : Çancers and myocardial infarction (MÏ) are two major causes of human mortality. Ôn the other hand, angiogenesis is a phenomenon having a basic role in the pathogenesis of both of them. Therefore, it seems possible to find a relationship between the occurrence of MÏ and cancer. There is limited number of relevant reports. Therefore in order to have more data, a case-control study was designed and performed in Sari in 1999-2000. Materials and methods : Âmong those being admitted in Ïmam khomeini and Fatemeh Zahra hospitals of Sari, 50 patients with pathologically confirmed cancer were selected randomly (known as the case group) and 50 other patients without history of cancer were matched with the case group for age, sex and history of cancer or MÏ and close relative (known as the control group). Then, data including confirmed history of MÏ and presence of some major risk factors (Diabetes Mellitus, Hypertension, Hyperlipidemia) were collected and analyzed by Çhi-square test. Results : Ôut of 50 case group patients, 8 had proven history of MÏ, while there were 4 patients with proven history of MÏ in the control group too, but this difference was not statistically significant. By sex discrimination, history of MÏ was positive in 6 women of the case group and 1 of the control group, the difference was statistically significant (P<0.05). There was no significant relationship between males of the two groups, and also there was not a significant difference between the two groups for the presence of MÏ risk factors as regard or regardless of sex. Çonclusion : Âccording to the results of this study, a statistically significant relationship was found between the occurrence of MÏ and cancers in women. Hence, despite the need for more studies about the relation between cancer and MÏ, more attention to this phenomenon is required in women.